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Services include - 24-hour physician-covered emergency department, Diabetes education, Full-service laboratory, Medical imaging services, Digital mammography, Physical therapy, Occupational therapy, Speech therapy, Radiology, and Medication disposal.

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

A multi-specialty health care clinic with a variety of specialties such as: cardiology; family practice; pediatrics; radiology; urology; orthopedics; general surgery; internal medicine; OB/GYN; palliative medicine; geriatric medicine; full service laboratory; prenatal care; pulmonology; nephrology; rheumatology; physical medicine; and diagnostic imaging center.

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

A primary care and family medicine clinic.

Services include skilled nursing, physical therapy, occupational therapy, speech therapy, personal care, dressing, medication assistance, lab draws, and home infusion therapy. Also specializes in providing home care after surgery.

Black Hills Urgent Care offers injury and illness care, immunizations and vaccinations, basic physicals and physicals for school, sports, and employment, and occupational medicine. COVID-19 tests are available.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Located on the Pine Ridge Reservation, it is an ambulatory care center with outpatient services. Services include primary care, pediatric, women's health, optometry, dental, behavioral health, podiatry, radiology, and laboratory tests.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Primary care and preventive care for adult women. Provides services such as allergy Injections, basic testing including EKG's for conditions of arteries and veins, bone density screening, care for common and specialized illnesses and injuries such as fractures, drug screening and substance abuse evaluations, immunizations, health screenings, laboratory services, stress tests, x-rays, ultrasound procedures, lesion removal, dermatology services, wound care, osteopathic manipulative treatment, pulmonary care, routine prenatal care, regular health maintenance exams and checkups, physicals required for the workplace or pre-surgical preparation, and hormone replacement, Counseling focused on individualized mental health treatment for adults and adolescents. Specialties in eating disorders, depression, anxiety, women's issues, life changes and adjustments, and medical nutrition therapy.

Provides clinic services such as primary care, women's health, men's health, physicals, preventative medicine, pediatric care, enhanced laboratory services, immunizations, and health education.

Provides quality home health care to residents of the Sioux Empire, Vermillion, and Chamberlain communities. Services offered include care for heart conditions, complex wound care, diabetes education and assessment, disease and symptom management, education on a newly diagnosed medical condition, home health aide, home infusion therapy education, home safety education, medication education, occupational therapy, pain management, pediatric care, physical therapy, postsurgical care, skilled nursing, speech therapy, and rehabilitation therapy while recovering from an orthopedic condition or hospital stay. They are most appropriate for individuals recently discharged from the hospital and are not fully recovered such as after surgery or new diagnosis, individuals recently diagnosed with an illness and needing education, and individuals who have a chronic condition that needs frequent clinical assessment such as diabetes, kidney, stroke, heart or lung disease.

Provides a full range of primary healthcare services including physical exams, chronic disease management, acute illness management, physicals, well child exams, children/adolescent/men/women healthcare services, immunizations, telemedicine related to medical and mental health needs, certified laboratory services, All Women Count services, assistance with Marketplace insurance enrollment, and allergy injections. Nurse triage available for after-hours calls. Situation will be assessed by a registered nurse with further guidance provided. Strives to meet the needs of all patients, including the underinsured and underserved and offers services at a reduced rate to those who qualify.

Featured health services include Avera QuickLabs, emergency and trauma, pharmacy, therapy and rehabilitation, pregnancy and birth, prenatal care, OB/GYN, radiology and imaging, respiratory and pulmonary care, sleep medicine, telemedicine, urgent care, urology, wellness and preventive care, women's health, and wound care.

Horizon Health - White River is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides a full range of primary healthcare services including physical exams, chronic disease management, acute illness management, physicals, well child exams, children/adolescent/men/women healthcare services, immunizations, telemedicine related to medical and mental health needs, certified laboratory services, All Women Count services, assistance with Marketplace insurance enrollment, and allergy injections. Nurse triage available for after-hours calls. Situation will be assessed by a registered nurse with further guidance provided. Strives to meet the needs of all patients, including the underinsured and underserved and offers services at a reduced rate to those who qualify.

Provides a full range of primary healthcare services including physical exams, chronic disease management, acute illness management, physicals, well child exams, children/adolescent/men/women healthcare services, immunizations, telemedicine related to medical and mental health needs, certified laboratory services, All Women Count services, assistance with Marketplace insurance enrollment, and allergy injections. Nurse triage available for after-hours calls. Situation will be assessed by a registered nurse with further guidance provided. Strives to meet the needs of all patients, including the underinsured and underserved and offers services at a reduced rate to those who qualify.

Horizon Health - Mission is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, prenatal care, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides quality home health care to residents of the Sioux Empire, Vermillion, and Chamberlain communities. Services offered include care for heart conditions, complex wound care, diabetes education and assessment, disease and symptom management, education on a newly diagnosed medical condition, home health aide, home infusion therapy education, home safety education, medication education, occupational therapy, pain management, pediatric care, physical therapy, postsurgical care, skilled nursing, speech therapy, and rehabilitation therapy while recovering from an orthopedic condition or hospital stay. They are most appropriate for individuals recently discharged from the hospital and are not fully recovered such as after surgery or new diagnosis, individuals recently diagnosed with an illness and needing education, and individuals who have a chronic condition that needs frequent clinical assessment such as diabetes, kidney, stroke, heart or lung disease.

Provides emergency care, pediatrics, family medicine, general practice medicine, inpatient and outpatient rehabilitation therapy, medical imaging, OBGYN, 3D mammography (Free mammogram and cancer screening program 'We've Got You Covered'), chemotherapy, laboratory services, internal medicine, general surgery, dialysis, home health, hospice, intensive care, outpatient treatment, same day surgery, orthopedic surgery, podiatric surgery, prenatal care, and swing bed.

The Avera Winner Medical Clinic is a member of the Avera McKennan Primary Care Network and Avera Health. Services include laboratory, x-ray, and Beltone hearing aid specialist on-site monthly.

Clinic services offered include Preventative Care, Pediatrics, Pregnancy Care, Women's Health, 3D Mammograms, Lab Work, and Imaging.

Providing clinical health services for all ages, including Medications for Opioid Use Disorder, senior care, maternity, pediatric, men's health, LGBTQ+ care, vaccinations, lab services, and telehealth visits. A Community Health Worker is also available to help coordinate services.

Provides a variety of medical services ranging from infants to older adults. These include general medical care, preventative health care, newborn/pediatric/adolescent/adult/geriatric care, OB/GYN, prenatal care, laboratory services, radiology, school and sports physicals, hospice care, orthopedic care, behavioral health, CT, and sleep studies.