Provides emergency care, pediatrics, family medicine, general practice medicine, inpatient and outpatient rehabilitation therapy, medical imaging, Women's Wellness Center (Obstetrics, gynecology and digital mammography), Digital mammography (Free mammogram program We've Got You Covered), Physicians Clinic (pediatrics, family medicine, obstetrics, urology, general surgery, orthopedics), chemotherapy, laboratory services, internal medicine, general surgery, dialysis, home health, hospice, intensive care, outpatient treatment, same day surgery, and swing bed.

The Woodrow Wilson Keeble Memorial Health Care Center is accredited by Joint Commission on Accreditation of Healthcare Organization, Inc. (JCAHO) serving Native American people living in or near Roberts County. Services include Behavioral Health, Dental, Diabetes Care, Health Promotion/Disease Prevention, Laboratory, Nursing, Radiology, Optometry, Pharmacy (Prescription Assistance - Enrolled members of a Native American tribe can get free prescriptions by visiting their local IHS), Primary Care, Public Health Nursing, Physical Therapy, Specialty Clinic (OB/GYN), Weight Loss/Nutrition, Well Child Care, Men/Women's Health, and Medication Disposal.

Licensed to operate 81 acute care hospital beds including Labor and Delivery, Telemetry, Critical Care, and general hospital. Hospital services also include a 24-hour emergency department, surgery capabilities, Interventional Cardiology, and services providing diagnostics and imaging services. PLHS also operates: Prairie Lakes Cancer Center, Prairie Lakes Brown Clinic, Prairie Lakes Mallard Pointe Surgical Center, dialysis units in Sisseton, SD, Watertown, SD and Ortonville, MN, Rehabilitation Services (PT and OT), and specialty services including Cardiology, Dermatology, Ear, Nose & Throat, General Surgery, Hospice, Home Care, Nephrology, Pulmonology, Urology, Wound Care, and Orthopedics.-