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A multi-specialty health care clinic with a variety of specialties such as: cardiology; family practice; pediatrics; radiology; urology; orthopedics; general surgery; internal medicine; OB/GYN; palliative medicine; geriatric medicine; full service laboratory; prenatal care; pulmonology; nephrology; rheumatology; physical medicine; and diagnostic imaging center.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

COVID Testing Option: ​Oyate Health Center Urgent Care 3200 Canyon Lake Drive 7:00am - 7:00pm (MT), 7 days a week Christmas Eve closes at 3pm (MT). Closed on Thanksgiving Day, and Christmas Day and New Year's Day. Oyate Health Center provides primary medical care, outpatient clinic, and urgent care. Additional outpatient services that are provided on site include optometry, pharmacy (Prescription Drug Take Back Site, blue drop-box by pharmacy), laboratory, radiology, dental, physical therapy, podiatry, and social services. Oyate Health Center has 2 sweat lodges. Please call for details. Oyate Health Center provides direct health services to Native Americans and provides contract health care services and referrals to those that are eligible within IHS requirements. This means that if a patient is enrolled in a federally recognized tribe or can prove lineage of descent of an enrolled tribal member; the patient may receive direct care services at Oyate Health Center. Prescription Assistance - Any Native American enrolled in a federally recognized tribe can receive prescription expense assistance at any IHS facility.

Hill City Clinic, a department of Custer Monument Hospital, is a primary care, family medicine clinic. Board-certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Services include Digital mammography, Family medicine, Geriatric care, Gynecology, Minor surgical procedures, Pediatrics, Wellness exams, and Vaccinations.

A Family Medicine clinic, providing medical services to patients in Huron and the surrounding area. Services include: vaccinations and flu shots, adult and childhood immunizations, family medicine; routine physicals: annual, school, pre-employment, work, and DOT certified exams; allergy and immunization: therapeutic injections, and allergy shot administration; women's health: pap tests, breast screening, contraception, and STI/STD testing; screening: in-house laboratory testing, bone density, cancer, diabetes, cholesterol, drug, alcohol, vision, and hearing; cardio health: EKG and blood pressure screening; pulmonary health: nebulizer treatments, pulmonary function testing; diabetes: screening, education, diet information, weight management, and medication management; minor surgery: mole/lesion removal, laceration repair, skin tag removal, wart removal, and liquid nitrogen treatment, joint injections and aspirations, cortisone injections and fluid removal, skin cancer screening, and imaging: x-rays, ultrasound, and bone density testing.

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

Horizon Health - Eagle Butte is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, prenatal care, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Clinic services include primary care, children's health, pregnancy and birth, radiology and imaging, laboratory and women's health. This location also offers sharps disposal.

A primary care, family medicine clinic that provides comprehensive care for the entire family through all phases of life, from childhood to senior years. Board certified physicians and physician assistants offer health care services sensitive to individual needs. Services include: outpatient counseling for adults and adolescents, family medicine, audiology/hearing aids, bone density screening, childhood & adult immunizations, general surgery, laboratory, OB/GYN, office-based surgery, sports & pre-employment physicals, and x-ray.

A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adult, and geriatric patients. Services include preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, radiology, and lab services.

Offering multi-specialty health care services such as 3D mammography, family medicine, lab, x-ray, and ultrasound services, obstetrics and gynecology (OBGYN), pediatrics, prenatal care, physical therapy, sexual health and intimacy care, and women's health services. Also offers behavioral health services such as dialectical behavioral therapy (DBT) and eye movement desensitization and reprocessing (EMDR) therapy.

Horizon Health - Martin Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, prenatal care, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

A primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Specialties include family medicine, internal medicine, childhood and adult immunizations, and sports and pre-employment physicals.

Horizon Health - Wessington Springs Medical is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Wessington Springs Dental provides a full range of family oral health services including preventative care (check ups, fillings), restorative and cosmetic dentistry (crowns, bridges) , endodontics, and oral surgery (root canals, extractions).

Horizon Health - De Smet Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

Provides adult medicine, women's health, obstetrics, pediatric medicine, physicals, wound care, minor surgeries, radiology, laboratory, disease management, rehabilitation and therapy services, and cardiology, podiatry, orthopedics, surgery outreach services.

Provides clinic services such as primary care, women's health, men's health, physicals, preventative medicine, pediatric care, enhanced laboratory services, immunizations, and health education.

Services include obstetrics with ultrasound, delivery with intrathecal block, pediatrics with inhalation therapy and IV therapy, family practice, geriatrics, disease management, hormone replacement therapy, and 24-hour emergency care and outpatient hospital.

Offers a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Located on the Pine Ridge Reservation, it is an ambulatory care center with outpatient services. Services include primary care, pediatric, women's health, optometry, dental, behavioral health, podiatry, radiology, and laboratory tests.

The Extended Care and Rehab Service Line includes the following services: Caregiver support group, spinal cord injury / disorder program, full suite of therapies, chiropractic care, integrative health services, adaptive sports, low vision and visually impaired services, inpatient community living center, pain management, whole health services, community living center, hospice/palliative Care, polytrauma/traumatic brain injury (TBI), geriatrics & extended care (GEC), medical foster home, and home health care.