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Featuring personalized primary care, laboratory tests offering blood drawing services, prescriptions are processed through the mail or My HealtheVet, Intensive Outpatient Program (IOP) for Substance Abuse Disorder and outpatient addictive disorder services.

Clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Horizon Health - De Smet Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Horizon Health - Elk Point is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Services include Walk-in Urgent Visits (for both medical and dental), Schedule and same day appointments, Family Practice and Internal Medicine Primary Care for adults, Dental Care for all ages (including teeth cleanings), Sexual and Reproductive Health Services, On-site lab and X-Rays, On-Site Pharmacy, and After-Hours On-Call Provider 365 days a year. Primary and Pediatric Medical Clinic: Most routine medical services and several specialized fields including: physicals, immunizations, preventative medicine, chronic disease management, and counseling. Well child checkups, vaccinations, general pediatric health care. Mental Health: Offers outpatient counseling and psychiatric services, to both children and adults. Case management is offered to adults and families. Dental Clinic: Provides emergency, preventive, and oral health care. Accepts Medicaid, Private Insurance, Medicare, free of charge for the homeless and on a sliding fee scale for uninsured. One Heart Clinic: Providing primary family care to patients with a focus on patients with a primary language of Spanish. Pharmacy: Convenient, on-site location, CHCBH patients are able to fill most of their medications the same day as appointment.

Offering a wide variety of services including immunizations, check-ups, sports physicals, lab work, minor procedures, and more.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Wall Monument Medical Clinic is a primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Services include Family medicine, Electrocardiogram, Laboratory, and Medical imaging.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

Located on the Pine Ridge Reservation, it is an ambulatory care center with outpatient services. Services include primary care, pediatric, women's health, optometry, dental, behavioral health, podiatry, radiology, and laboratory tests.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Clinic locations offer family care to Sioux Falls and the surrounding area. Provides a variety of services for family and primary care (including flu shots) as well as prenatal care and OB/GYN. Other health services include yearly checkups, treatment of minor illnesses, and management of chronic conditions.

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

A full service hospital and family medicine clinic located in the community of Aberdeen, SD. The facility provides acute, emergency, and medical care, full lab, with diagnostic testing, outpatient infusion, respiratory therapy, radiology, rehabilitation, diabetes care, pharmacy, flu shots, surgery, women's center/labor and delivery, oncology/cancer, and cardiology/heart.

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Provides primary care, Patient Centered Medical Home (PCMH) outpatient services, and Pharmacy.

A primary care and family medicine clinic. Services include Family medicine, Primary Care, Internal Medicine, Medical Imaging, Laboratory Services and Urgent Care.

A family practice and women's health clinic offering comprehensive care to newborns, pediatric patients, adult and geriatric patients, preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, and lab services.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Medical services that are offered include allergy, asthma, and immunology, dermatology, ear, nose, and throat, family medicine, gastroenterology, general surgery, internal medicine, interventional pain, ophthalmology, optometry, pediatrics, podiatry, and rheumatology.

Medical services that are offered include allergy, asthma, and immunology, dermatology, ear, nose, and throat, family medicine, gastroenterology, general surgery, internal medicine, interventional pain, ophthalmology, optometry, pediatrics, podiatry, and rheumatology.

Provides clinic services such as primary care, women's health, men's health, physicals, preventative medicine, pediatric care, enhanced laboratory services, immunizations, and health education.