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Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, the Browns Valley Clinic in Browns Valley, Minnesota, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), and Women's Health. The take-back site is available.

Offering multi-specialty health care services such as 3D mammography, family medicine, lab, x-ray, and ultrasound services, obstetrics and gynecology (OBGYN), pediatrics, physical therapy, sexual health and intimacy care, and women's health services. Also offers behavioral health services such as dialectical behavioral therapy (DBT) and eye movement desensitization and reprocessing (EMDR) therapy.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Bison Clinic is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adult, and geriatric patients. Services include preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, radiology, and lab services.

Services include cancer services/oncology, cardiology, chaplain services, diabetes care, diagnostic imaging, emergency and trauma care, home health and hospice, home medical equipment, occupational health, orthopedics, pediatrics, rehabilitation services, senior services, sports medicine, telemedicine, wellness services, women's specialty services, and family medicine.

Offers the following services: primary care, birth control, morning-after pill (emergency contraception), breast and chest exams including mammogram referrals if necessary, HIV testing, LGBTQ Services, men's health care, pregnancy testing and services, STD testing/treatment/vaccines, women's health care, gender affirming hormone therapy (GAHT), HPV vaccinations, Hepatitis B vaccinations, and Flu shots. Telehealth visits are available on Tuesdays for some of these services.

Featured health services include cancer care, blood diseases and disorders, brain and spine care, dentistry, emergency and trauma, heart and vascular care, infectious disease and public health, laboratory, nutrition, pain management, pregnancy and birth, Radiology and imaging, respiratory and pulmonary care, sleep medicine, surgery, telemedicine, therapy and rehabilitation, wellness and preventive care, women's health, and wound care.

Horizon Health - Fort Thompson is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Walk-in appointments welcome.

Providing family medicine (including flu shots).

Horizon Health - Yankton Medical offers Medical care (behavioral health, geriatric, chronic care management, DOT physicals, physical exams, family medicine, maternal health, family planning, sexually-transmitted disease testing, nursing, health education, immunizations, preventative services, well child exams, acute care, immunizations, lab/x-ray, and women's health). Also offers Certified Application Counselors for the Health Insurance Marketplace. Horizon Health - Yankton Dental offers dental care services include cleanings, dental exams, bridges, crowns, dentures, digital x-rays, emergencies, extractions, fillings, mouth guards, partials, root canals, sealants and spacers.

Offers the following services to males and females in their reproductive years on a sliding scale - male/female reproductive health exams, birth control services, sexually transmitted infection testing, treatment and education, pregnancy testing, and educational programs to community groups and schools on request, regarding sexually transmitted infections and birth control methods. *Due to Title X funding, parental consent is not required for those under 18.

A full service hospital providing hospital services, 24-hour emergency care, laboratory services, radiology services, cardiac rehab, physical, occupational and speech therapy services, wellness services, and wound care.

Offers a wide range of services in general medicine, family medicine, geriatrics, minor surgical procedures, and routine annual exams. Services include physicals and annual exams, pre-employment physicals, wellness exams, athletic physicals, access to various specialists, biopsies and minor surgical procedures, urine drug testing, immunizations, patient education, preventive healthcare, and routine pre-natal and obstetrics care.

Rural Health Clinic provides primary care including family medicine and ancillary services. Board Certified Physicians and Nurse Practitioners tailor health care services to each individual's needs. Services include family medicine, family wellness exams, fracture care, geriatric care, minor surgical procedures, pediatric care, prenatal/gynecology, and vaccinations.

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

An independent, nonprofit critical access hospital providing the following services: emergency care, cardiac rehabilitation services, coronary care, diabetes counseling, intensive care, in-patient services, obstetrics/childbirth services, occupational therapy, physical therapy, pulmonary care services, radiology services, respiratory therapy, sleep studies, swing bed program, surgical services, and on-site specialty providers (orthopedics, pain management, cardiology, urology, and audiology).

Avera Medical Group Brookings is a multi-specialty medical group providing clinic laboratory, digital mammography, imaging and x-ray, 3D mammography, ear, nose and throat, family practice, general surgery, infusion/chemotherapy, internal medicine, obstetrics & gynecology, orthopedics, outreach specialists, pediatrics, physical therapy, dermatology, podiatry, and urology. A Coordinated Care Team is available to help identify resource support for community and primary healthcare needs; facilitation and connection to long-term counseling services to meet mental health needs, and clinic based counseling for interim or short-term support needs.

Providing family medicine (including flu shots).

Horizon Health - Eagle Butte is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sponsored by Avera, Avera St. Luke's facilities include a hospital and comprehensive retirement communities in Aberdeen and Eureka, and clinics. Services include: addiction care (residential and outpatient services), behavioral health services (inpatient and outpatient), cancer services/medical oncology and radiation oncology, cardiology, dermatology, diabetes care, diagnostic imaging, emergency and trauma care, home health and hospice, Human Performance Center, hyperbaric oxygen treatments (wounds only), kidney dialysis, long-term care, nephrology, OB/GYN, occupational health, orthopedics, pain management, pediatrics, physical medicine and rehab, podiatry, primary care (family practice and internal medicine), primary care clinic (Groton, SD, and Ellendale, ND), pulmonology, same-day sick visit clinic, sleep lab, spine surgery, surgery, after-hours clinic, urology, wellness services, women's specialty services, and wound care.

A full service hospital and family medicine clinic located in the community of Chamberlain, SD. The facility provides acute, emergency, and medical care.

Sanford Vermillion Medical Center is a full service hospital and clinic providing the following services: 24-Hour Emergency Care, Ground and Air Ambulance support/access, medical, surgical, pediatric, and obstetrical care, outpatient nursing services (including chemotherapy), family medicine clinic, diagnostic services, home care and hospice programs, outpatient mental health counseling, rehabilitation therapies, respiratory care, acute care hours Saturday morning, Sunday afternoon, and weekday evenings, sports medicine, community health education, specialty outreach services (cardiology, diagnostic radiology, ENT surgery, general surgery, neurology, nephrology, oncology, orthopedics, podiatry, psychiatry, pulmonology, urology, and vascular surgery), and University of South Dakota student health services. Vermillion Medical Center has a teaching affiliation with USD Health Science Program.

Horizon Health - Mission is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Medical services provided include: Adult Medicine - annual checkups, wellness consultations, comprehensive evaluations, preventative care, and diagnostic services. Women's Health - annual health exams, pap smears, breast health services, and routine gynecological care. Obstetrics - prenatal and postpartum care in partnership with OB/GYN specialists. Minor Surgery - laceration repair, foreign body removal, wart removal, biopsies (skin or superficial lesions), excision of ingrown toenails, fractures and sprain care. X-Rays/Laboratory Services - some of the testing is done on site. Tests that cannot be performed on site are provided at Pioneer Memorial Hospital in Viborg. Referrals - connects patients with a specialist in any area Disease Management - monitor conditions such as hypertension, thyroid disease, diabetes, cardiac conditions, etc. Therapy services including speech, physical, and occupational

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.