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A multi-specialty health care clinic with a variety of specialties such as: cardiology; family practice; pediatrics; radiology; urology; orthopedics; general surgery; internal medicine; OB/GYN; palliative medicine; geriatric medicine; full service laboratory; prenatal care; pulmonology; nephrology; rheumatology; physical medicine; and diagnostic imaging center.

Coteau des Prairies (CDP) Health Care System is a 25-bed, critical access acute care, community non-profit hospital serving approximately 21,000 residents in the Glacial Lakes Region in north east South Dakota, and west central Minnesota. CDP Health Care System owns and operates the attached certified rural health clinic in Sisseton, and the Rosholt Clinic in Rosholt, South Dakota.​ Services available at Coteau des Prairies Hospital and Clinic include In-patient and out-patient surgery, Swing Beds, Emergency Room, Cardiac Rehab, Laboratory Services, Radiology, Mammography, Therapy Services, Fitness Center, Medication disposal, Diabetic Education, Telehealth, Medical-Assisted Treatment (MAT), Nutrition Services, and Women's Health. The take-back site is available.

Provides a variety of medical services ranging from infants to older adults. These include general medical care, preventative health care, newborn/pediatric/adolescent/adult/geriatric care, OB/GYN, prenatal care, laboratory services, radiology, school and sports physicals, hospice care, orthopedic care, behavioral health, CT, and sleep studies.

A full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

COVID Testing Option: ​Oyate Health Center Urgent Care 3200 Canyon Lake Drive 7:00am - 7:00pm (MT), 7 days a week Christmas Eve closes at 3pm (MT). Closed on Thanksgiving Day, and Christmas Day and New Year's Day. Oyate Health Center provides primary medical care, outpatient clinic, and urgent care. Additional outpatient services that are provided on site include optometry, pharmacy (Prescription Drug Take Back Site, blue drop-box by pharmacy), laboratory, radiology, dental, physical therapy, podiatry, and social services. Oyate Health Center has 2 sweat lodges. Please call for details. Oyate Health Center provides direct health services to Native Americans and provides contract health care services and referrals to those that are eligible within IHS requirements. This means that if a patient is enrolled in a federally recognized tribe or can prove lineage of descent of an enrolled tribal member; the patient may receive direct care services at Oyate Health Center. Prescription Assistance - Any Native American enrolled in a federally recognized tribe can receive prescription expense assistance at any IHS facility.

Offers the following services: primary care, birth control, morning-after pill (emergency contraception), breast and chest exams including mammogram referrals if necessary, HIV testing, LGBTQ Services, men's health care, pregnancy testing and services, STD testing/treatment/vaccines, women's health care, gender affirming hormone therapy (GAHT), HPV vaccinations, Hepatitis B vaccinations, and Flu shots. Telehealth visits are available on Tuesdays for some of these services.

Hill City Clinic, a department of Custer Monument Hospital, is a primary care, family medicine clinic. Board-certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Services include Digital mammography, Family medicine, Geriatric care, Gynecology, Minor surgical procedures, Pediatrics, Wellness exams, and Vaccinations.

Licensed to operate 81 acute care hospital beds including Labor and Delivery, Telemetry, Critical Care, and a general hospital. Hospital services also include a 24-hour emergency department, surgery capabilities, Interventional Cardiology, Cardiology, Dermatology, Ear, Nose, & Throat, Nephrology, Pulmonology, Urology, Rehabilitation Services (PT and OT), Wound Care, Orthopedics, and services providing diagnostics and imaging services. -

Sanford Health Mitchell offers the following specialties: 3D mammography, colonoscopy, family medicine, health coaching, immunizations, internal medicine, laboratory, MRI, nephrology, neurosurgery, OB/GYN, orthopedics, pediatric cardiology, physical medicine & rehabilitation, pulmonology, ultrasound, vascular care, vascular surgery, walk-in and x-ray.

Brookings Hospital is a licensed 49-bed hospital. Services include same day surgery/operating room, emergency room, inpatient care, obstetrics, prenatal care, and ancillary services - radiology, rehab/therapy, and laboratory. Full service hospital that provides both inpatient and outpatient care.

Horizon Health - Eagle Butte is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, prenatal care, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Clinic services include primary care, children's health, pregnancy and birth, radiology and imaging, laboratory and women's health. This location also offers sharps disposal.

A primary care, family medicine clinic that provides comprehensive care for the entire family through all phases of life, from childhood to senior years. Board certified physicians and physician assistants offer health care services sensitive to individual needs. Services include: outpatient counseling for adults and adolescents, family medicine, audiology/hearing aids, bone density screening, childhood & adult immunizations, general surgery, laboratory, OB/GYN, office-based surgery, sports & pre-employment physicals, and x-ray.

A family practice and women's health clinic offering comprehensive care to newborns, pediatrics, adult, and geriatric patients. Services include preventative care, annual examinations, Department of Transportation (DOT) examinations, immunizations, obstetrical care, women's health care, mental/behavioral health services, radiology, and lab services.

Offering multi-specialty health care services such as 3D mammography, family medicine, lab, x-ray, and ultrasound services, obstetrics and gynecology (OBGYN), pediatrics, prenatal care, physical therapy, sexual health and intimacy care, and women's health services. Also offers behavioral health services such as dialectical behavioral therapy (DBT) and eye movement desensitization and reprocessing (EMDR) therapy.

Horizon Health - Martin Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, prenatal care, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Horizon Health - Isabel is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Isabel is also a partner with the Department of Veterans Affairs (VA) Community Care Program.

Offers the following services to males and females in their reproductive years on a sliding scale - male/female reproductive health exams, birth control services, sexually transmitted infection testing, treatment and education, pregnancy testing, and educational programs to community groups and schools on request, regarding sexually transmitted infections and birth control methods. *Due to Title X funding, parental consent is not required for those under 18.

A primary care, family medicine clinic. Board certified physicians and physician assistants offer health care services sensitive to the individual needs of you and your family. Specialties include family medicine, internal medicine, childhood and adult immunizations, and sports and pre-employment physicals.

Horizon Health - Wessington Springs Medical is a full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT). Horizon Health - Wessington Springs Dental provides a full range of family oral health services including preventative care (check ups, fillings), restorative and cosmetic dentistry (crowns, bridges) , endodontics, and oral surgery (root canals, extractions).

Horizon Health - De Smet Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Horizon Health - Alcester Medical is full-service medical clinic offering the following services - preventative screenings, acute care, chronic care management, well child visits, men's and women's health, immunizations, family planning, lab/x-ray, patient education, care management, DOT exams, after-hours access to care, and Certified Application Counselors for the Health Insurance Marketplace. Also offers behavioral health services: medication management, counseling, case management, integrated care, addiction services, and Medication Assisted Therapy (MAT).

Sanford Webster Clinic is a community clinic for the whole family (Family Medicine), and has urgent health care hours as well.

Falls Community Health is a family practice medical clinic and dental clinic with emphasis on health promotion and disease prevention. The Community Health Center was established in 1979 with its goal being to remove the barriers, primarily financial, that exist and limit the access of lower income individuals or families seeking primary health care services.  ​Services for the general public include family health, lab radiology, well-child care, immunizations, family planning (including birth control, STD screening and treatment), patient education, and dental care. Services for established clinic patients include outpatient mental health and substance abuse counseling, psychiatry services, transportation assistance (transporter of last resort), and pharmacy assistance to clients of the Falls Community Health Care Clinic.

Providing a range of generalized and specialized services including a Sleep Center, Surgical Services, Pain Management, and Sports Medicine.